Hugh Laurie as Dr. Gregory House
Lisa Edelstein as Dr. Lisa Cuddy
Omar Epps as Dr. Eric Foreman
Robert Sean Leonard as Dr. James Wilson
Jennifer Morrison as Dr. Allison Cameron
Jesse Spencer as Dr. Robert Chase
Peter Jacobson as Dr. Chris Taub
Kal Penn as Dr. Lawrence Kutner
Olivia Wilde as Dr. Remy Hadley (aka Thirteen)
Salvator Xuureb as Jerry Harmon
Joanna Koulis as Samantha Harmon
Janice Allen as Sadie
Bobbin Bergstrom as Nurse

Vanessa Zima as Becca

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